DSP-6952 hydrobromide
CAS No. 1184661-33-3
DSP-6952 hydrobromide ( DSP6952;Minesapride )
Catalog No. M10627 CAS No. 1184661-33-3
DSP-6952 is a novel potent, selective, orally active 5-HT4 receptor partial agonist with Ki of 50-100 nM for human 5-HT4a/4b/4c.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 1323 | Get Quote |
|
50MG | 2682 | Get Quote |
|
100MG | 3600 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
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Product NameDSP-6952 hydrobromide
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NoteResearch use only, not for human use.
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Brief DescriptionDSP-6952 is a novel potent, selective, orally active 5-HT4 receptor partial agonist with Ki of 50-100 nM for human 5-HT4a/4b/4c.
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DescriptionDSP-6952 is a novel potent, selective, orally active 5-HT4 receptor partial agonist with Ki of 50-100 nM for human 5-HT4a/4b/4c; enhances gastric motility and causes colonic giant migrating contractions (GMCs) associated with defecation in conscious dogs, having ED50 value for inducing GMCs of 1.56mg/kg; rapidly increases fecal wet weight without increasing fluid content in mice (1-10mg/kg, p.o.).
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SynonymsDSP6952;Minesapride
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number1184661-33-3
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Formula Weight535.86
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Molecular FormulaC21H32BrClN4O5
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(NC[C@H]1CN(CC2CCN(C(CO)=O)CC2)CCO1)C3=CC(Cl)=C(N)C=C3OC.[H]Br.[H]O[H].[H]O[H]
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Chemical Name(S)-4-amino-5-chloro-N-((4-((1-(2-hydroxyacetyl)piperidin-4-yl)methyl)morpholin-2-yl)methyl)-2-methoxybenzamide hydrobromide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Mine Y, et al. Eur J Pharmacol. 2018 Feb 9;826:123-132.
2. Tsubouchi T, et al. Eur J Pharmacol. 2018 Mar 1;826:96-105.
2. Tsubouchi T, et al. Eur J Pharmacol. 2018 Mar 1;826:96-105.
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